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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MLLT6 All Species: 8.79
Human Site: S535 Identified Species: 19.33
UniProt: P55198 Number Species: 10
    Phosphosite Substitution
    Charge Score: -0.2
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P55198 NP_005928.2 1093 112076 S535 S S R T F G P S G S L P S L S
Chimpanzee Pan troglodytes XP_511438 1140 117178 S582 S S R T F G P S G S L P S L S
Rhesus Macaque Macaca mulatta XP_001083126 1096 112258 S538 A S R N F G P S G S L P S L S
Dog Lupus familis XP_850714 1066 109714 P532 I Y T S N K D P I S H G G S G
Cat Felis silvestris
Mouse Mus musculus O54826 1068 112946 G550 S M Q Y R H D G A C P T T T F
Rat Rattus norvegicus XP_239329 1051 107603 I519 Y T S N K D P I S H G G G M L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510168 1032 109035 V534 Y S S N D V A V S F P N A V S
Chicken Gallus gallus XP_418117 880 92966 R412 E D C S F G C R G T S P Q E S
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_001122343 521 55451 R52 P T G P W Y C R K C E S Q E R
Nematode Worm Caenorhab. elegans P34447 867 92171 V399 P A R N T T S V A S L L P P G
Sea Urchin Strong. purpuratus XP_794974 1041 109191 F545 R D M G I Y S F G Q R G V L A
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 90.7 98.9 94.2 N.A. 38.5 89.5 N.A. 32.8 54.7 N.A. N.A. N.A. N.A. 26.2 25.4 26.8
Protein Similarity: 100 92.1 99.3 95.6 N.A. 51.7 91.6 N.A. 46.9 62.5 N.A. N.A. N.A. N.A. 37.4 40.2 39.6
P-Site Identity: 100 100 86.6 6.6 N.A. 6.6 6.6 N.A. 13.3 33.3 N.A. N.A. N.A. N.A. 0 20 13.3
P-Site Similarity: 100 100 93.3 13.3 N.A. 20 20 N.A. 26.6 46.6 N.A. N.A. N.A. N.A. 13.3 26.6 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 10 0 0 0 0 10 0 19 0 0 0 10 0 10 % A
% Cys: 0 0 10 0 0 0 19 0 0 19 0 0 0 0 0 % C
% Asp: 0 19 0 0 10 10 19 0 0 0 0 0 0 0 0 % D
% Glu: 10 0 0 0 0 0 0 0 0 0 10 0 0 19 0 % E
% Phe: 0 0 0 0 37 0 0 10 0 10 0 0 0 0 10 % F
% Gly: 0 0 10 10 0 37 0 10 46 0 10 28 19 0 19 % G
% His: 0 0 0 0 0 10 0 0 0 10 10 0 0 0 0 % H
% Ile: 10 0 0 0 10 0 0 10 10 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 10 10 0 0 10 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 0 0 0 0 0 0 37 10 0 37 10 % L
% Met: 0 10 10 0 0 0 0 0 0 0 0 0 0 10 0 % M
% Asn: 0 0 0 37 10 0 0 0 0 0 0 10 0 0 0 % N
% Pro: 19 0 0 10 0 0 37 10 0 0 19 37 10 10 0 % P
% Gln: 0 0 10 0 0 0 0 0 0 10 0 0 19 0 0 % Q
% Arg: 10 0 37 0 10 0 0 19 0 0 10 0 0 0 10 % R
% Ser: 28 37 19 19 0 0 19 28 19 46 10 10 28 10 46 % S
% Thr: 0 19 10 19 10 10 0 0 0 10 0 10 10 10 0 % T
% Val: 0 0 0 0 0 10 0 19 0 0 0 0 10 10 0 % V
% Trp: 0 0 0 0 10 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 19 10 0 10 0 19 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _